Effect of dental amalgam and nickel alloys on T-lymphocytes: preliminary report.

Author: Eggleston DW.

Source: J Prosthet Dent.

Year: 1984

Comment:

This study finds that dental amalgam can potentially impact the immune system.

Abstract / Excerpt:

“Preliminary data suggest that dental amalgam and dental nickel alloys can adversely affect the quantity of T-lymphocytes. Human T-lymphocytes can recognize specific antigens, execute effector functions, and regulate the type and intensity of virtually all cellular and humoral immune responses. Normal immune function depends on a proper quantity, quality, and ratio of T-lymphocyte helper and suppressor subsets. Further research may determine the frequency and magnitude of T-lymphocyte reduction and alteration by dental materials.”

Citation:

Eggleston DW. Effect of dental amalgam and nickel alloys on T-lymphocytes: preliminary report. J Prosthet Dent. 1984; 51(5):617-23.