Mercury toxicity presenting as chronic fatigue, memory impairment and depression: diagnosis, treatment, susceptibility, and outcomes in a New Zealand general practice setting (1994-2006).

Author: Wojcik DP, Godfrey ME, Christie D, Haley BE.

Source: Neuro Endocrinol Lett.

Year: 2006

Comment:

This study tracks symptom alleviation after removal of mercury fillings in patients with fatigue, depression, and memory issues, and it also links a correlation between the APOE4 genotype and chronic mercury toxicity.

Abstract / Excerpt:

“In a group of 465 patients diagnosed as having chronic mercury toxicity (CMT), 32.3% had severe fatigue, 88.8% had memory loss, and 27.5% had depression. A significant correlation was found between CMT and the Apo-lipoprotein E4 genotype (p=0.001). An investigation into an additional 864 consecutively seen general practice patients, resulted in 30.3% having evidence consistent with CMT, and once again a significant correlation was found with the APO-E4 genotype (p=0.001). Removal of amalgam mercury fillings when combined with appropriate treatment resulted in a significant symptom reduction (p<0.001) to levels reported by healthy subjects.”

Citation:

Wojcik DP, Godfrey ME, Christie D, Haley BE. Mercury toxicity presenting as chronic fatigue, memory impairment and depression: diagnosis, treatment, susceptibility, and outcomes in a New Zealand general practice setting: 1994-2006. Neuro Endocrinol Lett. 2006; 27(4):415-423.