Bisphosphonate-related osteonecrosis of the jaw (BRONJ): 5 year experience in the treatment of 131 cases with ozone therapy.

Author: Agrillo A, Filiaci F, Ramieri V, Riccardi E, Quarato D, Rinna C, Gennaro P, Cascino F, Mitro V, Ungari C.

Source: Eur Rev Med Pharmacol Sci.

Year: 2012

Comment:

The authors conclude, "At the present time there are no major guidelines in international literature for the treatment of BRONJ, the Authors then propose a therapeutic protocol based upon minimally invasive surgery, antibiotic and anti mycotic therapy with the adoption of ozone as regenerating factor for tissues. In 90% of the cases the results confirmed the procedure with successful outcomes."

Abstract / Excerpt:

“AIM: The authors present their protocol based upon medical treatment,antibiotic and antimycotic, together with minimally invasive surgery and ozone therapy developed after a 5 year experience to assess the viability of this treatment.”

Citation:

Agrillo A, Filiaci F, Ramieri V, Riccardi E, Quarato D, Rinna C, Gennaro P, Cascino F, Mitro V, Ungari C.  Bisphosphonate-related osteonecrosis of the jaw (BRONJ): 5 year experience in the treatment of 131 cases with ozone therapy. Eur Rev Med Pharmacol Sci. 2012; 16(12):1741-7.