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So far Hoffman DJ, Pattee OH, Wiemeyer SN. has created 994 blog entries.

Effects of fluoride on screech owl reproduction: teratological evaluation, growth, and blood chemistry in hatchlings.

The effects on reproduction in screech owls (Otus asio) of chronic dietary sodium fluoride administration at 0, 40, and 200 ppm were examined. Fluoride at 40 ppm resulted in a significantly smaller egg volume, while 200 ppm also resulted in lower egg weights and lengths. Day-one hatchlings in the 200 ppm group weighed almost 10% less than controls and had shorter crown-rump lengths. No gross abnormalities were apparent. Skeletal clearing and staining revealed significantly shorter tibiotarsus lengths in the 40 ppm and 200 ppm groups and a shorter radius-ulna length in the 200 ppm group. By 7 days of age, body weights and lengths did not differ from controls, but the tibiotarsus in the 200 ppm group remained shorter. No significant differences were detected in hematocrit, hemoglobin, plasma calcium or alkaline phosphatase. Plasma phosphorus levels were higher in the 40 ppm group than in controls. These results, in combination with the findings of Pattee et al. [25], revealed significant impairment of overall reproduction, suggesting that sodium fluoride could cause slight to moderate reproduction disorders in owls in fluoride-polluted areas.

By |2018-07-23T17:58:45+00:00January 1st, 1985|Fluoride|

A model for recording mercury release from an amalgam surface.

The release rate of mercury from a conventional, a dispersed phase or a spherical high copper content amalgam under static conditions in stimulated or artificial saliva has been measured and found to decrease approximately exponentially with time. A higher initial release rate was observed for mercury in stimulated saliva than in artificial saliva during the in vitro experiments. In a pilot study corrosion current was recorded from an amalgam specimen immersed in saliva, and was found to decrease approximately exponentially with time. After brushing the surface of the amalgam during two subsequent periods, in a manner similar to toothbrushing, an increase in corrosion current was measured indicating the removal of loosely bound corrosion products. A model describing the periodical mercury release from an amalgam surface has been proposed.

By |2018-07-19T17:43:43+00:00January 1st, 1985|Mercury|

Quantization of nickel and beryllium leakage from base metal casting alloys.

Fourteen dental casting alloys were analyzed for release of nickel and beryllium into acidic salivary solutions in vitro. Corrosion rates of varying pH levels and time in solution were calculated through the 120-day level, and the possible significance of these rates to allergic reactions or other health hazards were postulated.

By |2018-08-25T15:40:08+00:00January 1st, 1985|Mercury|

Long-term corrosion studies in vitro of amalgams and casting alloys in contact.

One conventional amalgam and two amalgams with higher copper content were stored in contact with various dental casting alloys in phosphate-buffered 0.9% NaCl solution, pH 6, at 37 degrees C during 35 weeks. Every 7 weeks the solutions were changed, and the corrosion was measured by analyzing the solutions for the amount of Cu, Zn, Sn, Hg, Ag, Co, Cr, and Ni. In the first 7 weeks the amalgams immersed in contact with acrylic or Co-Cr alloys released small amounts of elements, whereas the release was larger when the amalgams were in contact with the gold alloys. During the rest of the experiment the release of elements tended towards the same level, independent of the casting alloy in contact. In general, the high copper amalgams released more corrosion products into the solutions than the conventional one. The release of corrosion products was strongly pH-dependent. Changing the solutions more often and saturating the solutions with oxygen decreased the amounts of Hg and Ag released.

By |2018-08-28T00:30:58+00:00January 1st, 1985|Mercury|

Salivary content of patients with subjective symptoms resembling galvanic pain.

Analyses of whole and parotid saliva were performed in ten patients with subjective symptoms resembling galvanic pain and in their eight asymptomatic counterparts. Salivary flow rates, protein, IgA, lysozyme, sodium, potassium, chloride, calcium phosphate, copper, and magnesium contents were measured. The concentrations of protein, sodium, chloride, and phosphate in the whole saliva of the patients with symptoms were significantly higher, but concentrations of calcium, magnesium, and IgA were lower than in the asymptomatic controls. In parotid saliva, too, protein, lysozyme, and calcium concentrations were significantly altered in patients with oral symptoms. The analysis of free amino acids serine, proline, glutamic acid + glutamine, and glycine in the whole saliva did not show any significant differences between the two groups studied. The results suggest the importance of salivary contents in the development of oral soreness. Such changes in the salivary constituents could modulate the amount and character of the salivary macromolecules absorbed onto the teeth. This could lead to passivation or activation of the surfaces in metallic restorations and consequently to the onset of the intraoral electric currents.

By |2018-08-30T22:23:37+00:00January 1st, 1984|Other|

Metabolism of degradation/corrosion products from tissue—material interactions.

This paper relates materials science, physiology, biochemistry, pharmacology, immunology, pathology and toxicology to the study of metabolism of degradation and corrosion products arising from tissue/material interactions. The mechanisms of absorption and distribution of released substances, either in solution or as particles, are considered together with their related chemistry. The importance of immune processes is discussed and their potential use for immunological analysis is illustrated by reference to nickel and mercury as used in the oral cavity.

By |2018-08-25T21:46:59+00:00January 1st, 1984|Other|

Further observations on dental parameters of trigeminal and atypical facial neuralgias.

One hundred thirty-one patients with primary trigeminal neuralgia and 77 patients with atypical facial neuralgia or pain were treated by oral surgical procedures, with complete or almost complete pain remission in 88% of the cases and without persistent residual anesthesias, dysesthesias, or dysalgesias. The following conditions were related to patients’ pain perceptions: cavities in alveolar bone at tooth extraction sites, bone fistulas, periodontal infections, and maxillary sinus infections draining into alveolar bone. The bone cavities and fistulas mentioned above were usually not visualized by standard x-ray diagnostic procedures, and their detection required a new diagnostic approach which is described. Microbiologic findings indicated involvement of a mixed, variable flora in the above conditions. Histopathologic observations of scrapings from involved bone showed a variable incidence of bone necrosis, predominantly chronic inflammatory cell populations and fibrous tissue.

By |2018-08-29T21:32:45+00:00January 1st, 1984|Other|

Electrogalvanically-induced contact allergy of the oral mucosa: Report of a case.

A 69-year-old white female presented bilateral lesions of the oral mucosa possibly related to electrogalvanism. The lesions were histologically characterized as lichen planus and as mild epithelial dysplasia on the left and right sides, respectively. They disappeared after removing amalgam restorations opposing the lesions. Epicutaneous patch tests and lymphocyte-transformation tests showed that the patient suffered from a contact allergy to mercury compounds, indicating this as a mechanism by which electrogalvanism may induce lesions of the oral mucosa.

By |2018-08-27T20:50:02+00:00January 1st, 1984|Mercury|

Clinical study of patients referred for investigation regarding so‐called oral galvanism.

Fifty-four patients referred to the Faculty of Odontology, University of Umeå, for investigation regarding “oral galvanism” were subjected to a general oral investigation. In addition the following parameters were studied: the highest calculated current between two metallic restorations in contact and the electrogustometrically determined threshold value for each person. No differences were found regarding these two parameters between the patients and a control group consisting of 15 persons. However, the general oral investigation had revealed that a relatively large number of patients had periodontal conditions which, together with mucous membrane affections and hypersensitivity reactions could explain some of the unpleasant sensations which bothered them. Furthermore, the results of a stomatognathic investigation which will be presented separately revealed that about three fourths of the patients needed treatment for their stomatognathic and/or temporomandibular joint conditions.

By |2018-08-26T18:46:34+00:00January 1st, 1984|Mercury|

Charging people’s batteries.

Galvanism is seldom mentioned to the dental student, yet nearly every dentist alters a patient’s galvanic current every time he treats him. Galvanism is electrical current produced by placing dissimilar metals inan electrolyte. Saliva is the electrolyte. The dental dissimilar metal list is seemingly inexhaustive. We place copper, tin, zinc, mercury, silver, gold, platinum, irridium, indium, paladium, cobalt, chromium, nickle and baryllium into this electrolyte. A battery is produced. Electrical current is generated. Electricity doesn’t just exist. It is the simultaneous biproduct of a chemical reaction between the various phases of metallic interaction in the mouth. As electrical current is generated, various ions of these metals are emitted into the saliva. Many of these metals, or their corrosion products, are known toxins. Among them is mercury.

By |2018-08-26T15:56:27+00:00January 1st, 1984|Mercury|
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