Author: Ito T, Mori G, Oda Y, Hirano T, Sasaki H, Honma S, Furuya Y, Yajima Y
Source: International Journal of Implant Dentistry.
Year: 2021
Comment:
Abstract / Excerpt:
Objective: The mechanisms underlying the onset and progression of peri-implantitis are similar to those of periodontitis, and the causative bacteria are believed to similar. Previous studies support an association between peri-implantitis and periodontal pathogen. Thus, we investigated the bacterial flora of peri-implantitis patients in comparison to those of healthy implant and periodontitis patients.
Materials and methods: In total, 70 patients visiting Tokyo Dental College Chiba Hospital were divided into four groups: healthy, periodontitis, healthy implant, and peri-implantitis. For each group, the following five periodontal pathogens were detected using real-time polymerase chain reaction: Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Tannerella forsythia, Treponema denticola, and Prevotella intermedia.
Results: The average copy number of total bacteria was significantly higher in the periodontitis group than in the other groups. P. gingivalis was detected in the periodontitis and peri-implantitis groups at levels as high as 18.92% and 12.29%, respectively, and P. intermedia was found in the peri-implantitis group at a rate of 2.06%. Nevertheless, periodontal pathogens were generally detected at lower levels in the peri-implantitis group than in the periodontitis group.
Conclusion: We found lower bacterial counts in the peri-implantitis group relative to the periodontitis group. Our results suggest that the peri-implant tissue is less resistant to bacteria, so even a small number of bacteria can be a risk factor for peri-implantitis and the causative agent of peri-implantitis can be bacteria other than periodontal pathogen.
Citation: Ito T, Mori G, Oda Y, Hirano T, Sasaki H, Honma S, Furuya Y, Yajima Y. Clinical evaluation of periodontal pathogen levels by real-time polymerase chain reaction in peri-implantitis patients. International Journal of Implant Dentistry. 2021;7(1):1-7.