Author: Bralić M, Buljac M, Prkić A, Buzuk M, Brinić S.
Source: Int. J. Electrochem. Sci.
Year: 2015
Comment:
Abstract / Excerpt:
Pharmaceutical products for oral hygiene encompass several different formulations including toothpastes and pills. In these products, fluorides can be added in several different forms, such as sodium fluoride, sodium monofluorophosphate, tin fluoride, or in the form of different amines. This paper describes the potentiometric method with flow injection and continuous analysis for determination of hydrolysis of sodium monofluorophosphate and fluoride in the samples of toothpastes and pills. The measurements were performed in a home-made cell under appropriate flow conditions (2.86 mL min–1, 0.2 mL samples, 10–6 M sodium fluoride and Ac-buffer pH=5.5). Na2FPO3 complete hydrolyzed at a concentration of 1×10–4 mol L–1 by addition of 1.0 mL 6.0 M HCl in the measurements with the FIA. Measurements carried out with CA shows that even after addition of 4.0 mL 6.0 M HCl does not come to a complete hydrolysis Na2FPO3. Obtained results show that in measurements performed with FIA errors ranged from 2.21 to 9.60 %, while errors are around 30% in the measurements with CA.
Citation: Bralić M, Buljac M, Prkić A, Buzuk M, Brinić S. Determination Fluoride in Products for Oral Hygiene Using Flow-Injection (FIA) and Continuous Analysis (CA) with Home-Made FISE. Int. J. Electrochem. Sci. 2015; 10:2253-64.