Author: Dave VK, Cross D

Source: Contact Dermatitis

Year: 1989

Comment:

Abstract / Excerpt:

The various defects in cell-mediated immunity in psoriasis might also involve a loss of tolerance to nickel, high levels of which have been detected in psoriatic keratin (I). No data is available on the frequency of nickel sensitivity in psoriasis. A nickel induced psoriatic response strictly limited to the site of contact, with no evidence of the disease elsewhere, is rarely detected in this unit. A preliminary study was therefore undertaken to assess the frequency of concurrent nickel-induced psoriasis, especially in young women.

Citation: Dave VK, Cross D. Non‐occupatonal metal‐related contact in women with psoriasis. Contact Dermatitis. 1989;21(3):194-206