Author: Tomka M, Machovkova A, Pelclova D, Petanova J, Arenbergerova M, Prochazkova J.
Source: Oral Surg Oral Med Oral Pathol Oral Radiol Endod.
Year: 2011
Comment:
In this study, patients allergic to the mercury in their dental amalgam fillings recovered after removal.
Abstract / Excerpt:
“Orofacial granulomatosis is a clinicopathologic entity characterized by chronic swelling of the lip and possible soft tissues in the orofacial region owing to granulomatous inflammation of unknown cause. We present 3 cases of orofacial granulomatosis associated with allergic contact dermatitis to dental materials. Previous treatment with corticosteroids did not have any therapeutic effect. Patch testing revealed a positive reaction to several allergens, including dental amalgam and mercury in 2 cases. A lymphocyte transformation test modified for metals was used to evaluate lymphocyte reactivity. After the removal of the suspected allergens, all patients experienced recovery within 1 month, with the exception of the lip swelling, which gradually subsided over several months.”
Citation:
Tomka M, Machovkova A, Pelclova D, Petanova J, Arenbergerova M, Prochazkova J. Orofacial granulomatosis associated with hypersensitivity to dental amalgam. Science Direct. 2011; 112(3):335-341.