Author: Clarkson TW.
Source: Adv Dent Res.
Year: 1992
Comment:
This article about risk assessment uses dental amalgam fillings as an example and finds that they are a significant source of human exposure, although the author notes that the paper is not a final word on amalgam fillings.
Abstract / Excerpt:
“This review discusses the basic principles of risk assessment as used in general toxicology and in monitoring side-effects of therapeutic treatments. It also outlines how these principles may apply to assessment of biological reactions to dental restorative materials. Mercury exposure from amalgam fillings is used as an example. The calculations performed are intended only as illustrations, and many other factors must be taken into account. Thus, the calculations are not intended as the last word in risk assessment of amalgam fillings.”
Citation:
Clarkson TW. Principles of risk assessment. Adv Dent Res. 1992; 6(1):22-27.