Author: Hornos Carneiro MF, Morais C, Small DM, Vesey DA, Barbosa F Jr, Gobe GC.
Source: Environ Toxicol.
Year: 2014
Comment:
Abstract / Excerpt:
“This is the first report about kidney cell death and pro-fibrotic mechanisms promoted by thimerosal. Collectively, these in vitro results demonstrate that (1) thimerosal induces kidney epithelial cell apoptosis via upregulating Bax and the mitochondrial apoptotic pathway, and (2) thimerosal is a potential pro-fibrotic agent in human kidney cells. We suggest that new evidence on toxicity as well as continuous surveillance in terms of fibrogenesis is required concerning thimerosal use.”
Citation:
Hornos Carneiro MF, Morais C, Small DM, Vesey DA, Barbosa F, Gobe GC. Thimerosal induces apoptotic and fibrotic changes to kidney epithelial cells in vitro. Environ Toxicol. 2014.