Mercurial necrosis resulting from amalgam fillings.
“Mercurial necrosis is a field of pathology which has not received the investigation it deserves by the medical profession. While the poisonous effects of mercury have so long been recognized that I need take no time in rehearsing them, yet there are certain causes affecting the nerve centres which demand more thorough investigation than has yet been given. In presenting this subject to the Society for consideration I want to show that by the use of amalgam in filling teeth there is a possibility of mercurial poisoning, which seriously affects the nerve-centres, impairs locomotion by heaviness of limb and stiffness of joint, gives rise to obstinate diseases of the skin, and makes a mental wreck of its victim, whose imaginations and hallucinations are more than my pen can describe.”